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Better Living Through Well Being

This summer brings many reasons to celebrate - that a majority of our U.S. population is now fully vaccinated (60%) , our economy is more fully opening up with people frequenting restaurants, shops and recreation centers again, and people are able to feel the joy of gathering with friends and families - yet there are still good reasons to remain vigilant in guarding against the COVID-19 disease.

Vaccination coverage is not equal across the country with some states and counties with fairly low protection, and we are still 20-25% short of reaching herd immunity. The highly transmissible and potentially lethal Delta variant has now become the dominant mutation of the SARS-CoV-2 coronavirus here. Efforts continue to make COVID-19 vaccinations freely available and accessible to anyone, both here in the U.S. and globally in countries where rates of protection against the virus are still very low.

In this global fast-moving society where a powerful virus can continue to migrate and mutate into more powerful variations indefinitely, no one will be completely safe until everyone is safe. The COVID-19 pandemic will not be over until it is really over, and it is within our reach, helped by science and public health wisdom, to keep it, and other yet-to-be-discovered threats, safely eradicated.

When it comes to forces of nature there are limits to what humans can do to change things, but now is a time when we can all hope that common sense will prevail, and we will each act responsibly to do what is in our power to do. Then, true healing and recovery can happen for the whole world.


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Research scientists have discovered distinctive features of SARS-CoV-2-specific T-cells that can help predict patients’ recovery from severe COVID-19. These unique T-cell signatures may help them understand why some patients succumb to severe COVID-19 while others recover. In this clinical study the scientists were able to examine blood samples taken at different times during the patients’ stay in the ICU. In order to understand the cause of fatalities, they were able to compare fatal to non-fatal cases. Using a technique that distinguishes the many types of T-cells circulating in the body, the scientists found profound differences between the ICU patients’ T-cell response to the virus.

Based on these findings as outlined in the study, doctors might be able to predict the course of illness and better effect recovery from severe COVID-19. However, the scientists caution that the findings show correlations, not causes. The immune system is complex, with many moving parts and possible interactions between them. Proving the cause of fatality will require further studies.

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Concerned that widespread unwillingness to receive the COVID-19 vaccine is threatening herd immunity in countries like the United States, the United Nations Institute for Training and Research has formed a public/private alliance with businesses and local government entities in a toolkit supporting local vaccine uptake promotion efforts. Vaccine hesitancy threatens to delay the resumption of the daily activities that would lead to much-needed economic recovery globally. This toolkit will help clarify what government entities can offer, from knowledge of the communities they serve, to public outreach, to event support, as well as how they can begin the public-private partnership process.

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COVI-VAC, a new COVID-19 vaccine candidate created to be administered intranasally, has just completed its Phase 1 clinical trial. Early results show promise in the efficacy of this novel vaccine in the degree of its synthetic genetic match with the wild SARS-CoV-2 virus in all structural ways that matter for the immune system response, including all the proteins of the target and not just the spike protein. It will be capable of stimulating a complete, robust humoral and cell-mediated response and increased likelihood of covering variants.

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New data showing the efficacy of the Johnson and Johnson COVID-19 vaccine show that a single dose generated neutralizing antibodies against a range of SARS-CoV-2 variants of concern, which increased over time, including against the increasingly prevalent and more transmissable Delta variant, the partially neutralization-resistant Beta, the Gamma variants and others, including the original strain. Data showed that T-cell responses - including CD8+ T-cells that seek out and destroy infected cells - persisted over the eight-month timeframe examined.

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Other articles of interest in this TMIS eNewsletter for Summer 2021:

* New unconventional approach to carbon sequestration will help mitigate climate change by capturing carbon as a solid form and recycling it back into the earth across U.S. farmland, simultaneously addressing global warming and bolstering crops.

* Leadership consultants respond to a potential mass exodus of employees from the workplace following on the past year’s opportunity to rethink what is valuable.

* Businesses may need to step up to the challenge to meet the new hygiene expectations of post-pandemic work life.

* Global chemical company accomplishes milestone in closing the loop for a circular economy designed for recycling used plastics and also certified renewable products from bio-based feedstock.

* Trends in electric vehicle market demand more effective thermal management systems, solutions, and materials.

* ‘National Warrior Call Day’ resolution is presented to Congress.

* Aromatherapy calming mist relaxes even the most restless infants and relieves parents of stress.

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I am grateful to be in a collaborative business with many talented and skilled professionals. Additional feedback and recommendations for our services at TM Information Services are always welcome.

- Mary Michele McLaughlin


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