Spring Issue April 2024
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Better Living Through Well Being

What I’m about to tell you is a matter of life and death. If the soil dies we die.” - opening narration of documentary film “Common Ground.”

Regenerative farming practices based on regenerative agriculture aim to transform our food system for better health and better economy. Regenerative agriculture restores degraded soils using practices such as adaptive grazing, no-till planting, and the elimination of or limited use of pesticides and synthetic fertilizers that harm the environment. It focuses on topsoil regeneration, improving the water cycle, and sequestering atmospheric carbon into soils, helping them absorb and retain more water, becoming more drought resistant and slowing global warming.

These practices have been around since ancient times. Yet, history shows that many civilizations failed due to mismanagement of the land. Now again, we have the opportunity to build a bustling food economy, greatly impact climate change, enable farmers to save huge amounts of money and build prosperity. Regenerative agriculture holds the potential to reindustrialize middle America through bringing back sustainable farming practices and restoring soil health.

Transitioning from conventional to regenerative farming may involve significant initial investment and learning curve, but it may ultimately be more profitable because the system can lead to lower costs, the ability to grow higher value crops, greater diversity of foods produced and harvested, and access to new markets.

The 2020 documentary film “Kiss the Ground” begins with narrator Woody Harrelson saying that in the face of overwhelming warnings about climate change he’s given up. Then he asks, “But what if there was another path?” He says there is a story of a simple solution, a way to heal our planet and keep our species off the extinction list. The solution he’s talking about is right under our feet and as old as dirt. Due to its vast scale and its ability to sequester immense quantities of greenhouse gases, soil could be the one thing that can balance our climate, replenish our fresh water supplies and feed the world. “That’s why some people are racing to save our soil in hopes our soil just might save us.” (See the trailer or full movie here on YouTube.)

The follow-up documentary “Common Ground” is now being screened at major venues in the United States. See the trailer here.


Increasingly frequent and severe extreme weather events in Western North America driven by changes in major circulation patterns is the focus of a new study published in the journal Nature. The study shows that greenhouse gas emissions play a significant role in driving these shifts. The relationship change between three major teleconnection pathway patterns is traced to enhanced upper-level ridges across western North America, reflecting a reinforced winter stationary wave in the jet stream. This has been contributing to recent more frequent extreme weather events in the region.


A new study published in the journal Science discovered a mechanism used by the brain to determine which memories the brain makes permanent. Interestingly, the study finds it is the pauses in between periods of paying attention to something that the brain’s natural tagging mechanism takes place, and not during active sensory experience or movement, so that these memories are then encoded during sleep. It is the switch in awareness from an exploratory to an idle pattern that enables the brain mechanism to occur. In this manner, hippocampal “place cells” firing in a specific order can encode every room we enter, and by playing back the recorded event during sleep, strengthen the cells’ connections for future recall.


Hundreds of concepts of electric flying cars have been introduced in recent years. Very few have actually flown or have any outlook for commercial launch or operation. The years leading up to 2024, however, saw some electric vertical take-off and landing (eVTOL) aircraft achieve the type certification required to begin commercial passenger operation. Now it appears as though eVTOLs are becoming a feasible reality. Many challenges will need to be addressed, including developing batteries capable of sustaining electric vertical takeoff and landing.

A new report, “Air Taxis: Electric Vertical Take-off and Landing (eVTOL) Aircraft 2024-2044: Technologies, Players,” provides comprehensive detail from the basic pros and cons of the different eVTOL aircraft design architecture and opportunities in key enabling technologies.

A free-to-attend webinar will be held on the topic on Wednesday, May 1, 2024 - “Unlocking the Skies: The Promise of eVTOLs and Urban Mobility.”


Other articles of interest in this TMIS eNewsletter for Spring 2024:

* Groundbreaking documentary to shed light on a familiar yet shrouded silent epidemic, “The M Factor: Shredding the Silence on Menopause,” debuts October 5.

* Four-day workweek pilot reveals an innovative blueprint for a flexible workweek and thriving workplace.

*Diverse approaches to plant-based leather technologies seek to create a revolution in the leather industry.

* North American property business aims to reduce carbon emissions by 42% in 2030 with its Pathway to NetZero approach.

* Art of Living Social Projects restores polluted lake and surrounding landscape to ecological balance through nature-based interventions.

* Clinical trial assessing impact of a Fasting Mimicking Diet on Type 2 Diabetes delivers compelling evidence to support its integration into care management.

* Compound 11c, an novel drug candidate to combat fatty liver disease, paves the way for advancing treatment.


I am grateful to be in a collaborative business with many talented and skilled professionals. Your feedback is always welcome.

- Mary Michele McLaughlin

From the Front Page of TMIS News
Click on links below to view Full Stories.

Global Lifestyle Brand Announces Partnership with Global Environmental Non-Profit Kiss the Ground to Expand on Their Commitment to Regenerative Agriculture
Philadelphia, Pennsylvaniia

Anthropologie, the global lifestyle brand, has announced their partnership with Kiss the Ground, the leading voice of the regenerative agriculture and soil health movement. Through this exciting partnership, kicking off during Earth Month, Anthropologie hopes to improve awareness, education, and engagement around regenerative agriculture and how it contributes to a healthier planet for all.

Anthropologie's A Greater Good platform outlines the brand's priority of being a force for good in better service to our planet, its people, and its products and details their journey to becoming more environmentally responsible and socially conscious. Through conservation initiatives, partnering with a diverse array of non-profit partners, and working to ensure the products they sell are ethically sourced, the brand hopes to incite meaningful change.

"We are incredibly inspired by the work our friends at Kiss the Ground have been doing and are in awe of their ability to inspire millions of people across the country to participate in the regenerative movement," says Elizabeth Preis, Global Chief Marketing Officer of Anthropologie Group. "We're thrilled to kick off Earth Month by announcing this partnership, amplifying the essential work they are doing to protect our planet and combat climate change, and to motivate engagement across our community to do the same."

Full Story

Researchers Find the Link Between Human Activity and Shifting Weather Patterns in Western North America
Gwangju, South Korea

Western North America seems to be experiencing more extreme weather events more frequently. From scorching droughts to torrential floods, the climate is changing rapidly, with no signs of slowing down. From 2011 to 2015, California and neighboring states experienced extended periods of drought, while 2017 saw heavy rains trigger catastrophic floods.

These events are linked to specific weather patterns. The atmosphere is like a network of interconnected pathways that determine how weather systems move and interact across the globe. In the Northern Hemisphere, there are three such major teleconnection patterns that affect winter conditions: the Pacific North American pattern (PNA), the North Atlantic Oscillation (NAO), and the North American winter dipole (NAWD). However, the understanding of how these patterns change over time and their connection to climate change remains limited.

To better understand this phenomenon, a group of scientists led by Professor of Earth Sciences and Environmental Engineering Jin-Ho Yoon and including Ph.D. student Jueun Lee from the Gwangju Institute of Science and Technology recently conducted a study to examine the reasons behind changes in these patterns. Their findings have been published in npj Climate and Atmospheric Science on 7 March 2024.

Full Story

Mechanism Found to Determine which Memories Last
New York, New York

Neuroscientists have established in recent decades the idea that some of each day's experiences are converted by the brain into permanent memories during sleep the same night. Now, a new study proposes a mechanism that determines which memories are tagged as important enough to linger in the brain until sleep makes them permanent.

Led by researchers at NYU Grossman School of Medicine, the new study revolves around brain cells called neurons that "fire" -- or bring about swings in the balance of their positive and negative charges -- to transmit electrical signals that encode memories. Large groups of neurons in a brain region called the hippocampus fire together in rhythmic cycles, creating sequences of signals within milliseconds of each other that can encode complex information.

Called "sharp wave-ripples," these "shouts" to the rest of the brain represent the near-simultaneous firing of 15 percent of hippocampal neurons, and are named for the shape they take when their activity is captured by electrodes and recorded on a graph.  

While past studies had linked ripples with memory formation during sleep, the new study, published online in the journal Science on March 28, found that daytime events followed immediately by five to 20 sharp wave-ripples are replayed more during sleep and so consolidated into permanent memories. Events followed by very few or no sharp wave-ripples failed to form lasting memories.

Full Story

Taxiing For Takeoff: The Promise of eVTOLs, Reports IDTechEx
Boston, Massachusetts

Flying cars are very easy to hype. Most images of the future almost always include mass mobility in the air. It is one of the staples of any depiction of advanced modern societies and a trope of almost every science fiction movie or book (however dystopian). It is an exciting time where the level of technological advancement is reaching the stage of making electric vertical take-off and landing (eVTOL) aircraft a feasible reality.

However, considerable advancements, such as in battery energy density and charging capabilities, distributed electric propulsion systems, composite materials, and mass aircraft manufacture, are still required to make widespread deployment a reality. There are also many challenges not related to the technical feasibility of making an eVTOL fly, which will also need to be addressed, including certification of aircraft and parts, regulation of operations, public acceptance, and the development of ground infrastructure. IDTechEx's new report "Air Taxis: Electric Vertical Take-Off and Landing (eVTOL) Aircraft 2024-2044: Technologies, Players" is intended to help companies understand the exciting emerging urban air mobility (UAM) market. 

Many of the world's largest aerospace and automotive companies are ramping up their interest in eVTOL aircraft, recognizing it as a potentially disruptive new transport mode. The major aerospace suppliers, RTX Corporation, GE, SAFRAN, and Honeywell, are all investing in eVTOL-related technologies, including electric and hybrid-electric powertrain components, systems for autonomous flight, and advanced air traffic management systems. Furthermore, composite material manufacturers like Toray and Hexcel have been working with OEMs on the advanced lightweight materials required for several facets of eVTOL design. The automotive industry is also taking an interest, with Toyota, Hyundai, Stellantis, XPeng, Suzuki, and Honda all funding, collaborating on, or conducting their own eVTOL projects.

Full Story

The M Factor Film exploring menopause debuts October 18
Los Angeles, California

The film by Emmy-Award-winning filmmaker Jacoba Atlas and executive producers, Emmy Award-winning journalist Tamsen Fadal, Denise Pines, and Emmy Award-winning Joanne LaMarca athisen premieres on PBS October 18th, coinciding with World Menopause Day. Despite its universality, menopause has remained shrouded in stigma, silence and misunderstanding, contributing to the broader women's health crisis.

"The M Factor" features renowned doctors like Dr. Sharon Malone, M.D. FACOG, NCMP, and Neuroscientist Dr. Lisa Mosconi, leading advocates for women's health addressing timeless questions that have long plagued women, helping to enhance their quality of life. Women of all walks of life open up about the physical and mental anguish they live with every day. Doctors and policymakers speak out on the changes that need to be made, especially in the workplace where roughly 44% of women are over the age of 45. The film also sheds light on disparities faced by Black and Brown women as they assess their treatment options. 

Menopause represents a significant transition in women's lives that can have long-term consequences from cardiovascular disease and bone loss to dementia.  Despite its impact, the healthcare system inadequately prepares physicians to address menopause and its symptoms. That needs to change, and this is the beginning.

Full Story

Four-Day Workweek Pilot Reveals a Winning Formula for Achieving Business Success Without Sacrificing Employee Well-being
Phoenix, Arizona

Exos, the industry-leading performance coaching company that is helping organizations reimagine the future of work, has released the results of their four-day workweek pilot. Collected in partnership with the Wharton School of Business, the data reveal that pro-recovery practices can support employee well-being and sustain workplace effectiveness.

Last spring, Exos released the evidence-based Readiness Culture Code as a tool to help coach their employees to think differently about how they approach work. Accompanying this was the announcement of a four-day workweek pilot, which was complimented by the implementation of intentional scheduling, meeting auditing, daily microbreaks, and other tactics aimed at maintaining business effectiveness while adding recovery and flexibility into each employee's day.

The pilot results showcase how Exos' data-informed methodology and approach could be a solution for other employers looking to reform their workplace, reverse the exhaustion modern employees are facing, and retain top talent. Key learnings from the study include:

Full Story

Plant-based Leather: IDTechEx Discusses if It's a Revolution in the Leather Industry
Boston, Massachusetts

Plant feedstocks are the biggest focus of companies entering the emerging alternative leather market. Companies are utilizing a very diverse selection of input feedstocks, including bamboo, grapes, apple skin, cactus, and pineapple leaves. Additionally, there are several different approaches to the incorporation of plant-based materials and the general manufacturing process.

The emergence of a wide field of competing feedstocks from different sources raises the question of which feedstock comes to dominate the field of plant-based leather and whether the feedstock would support the scale-up of the production of that plant-based leather. The question of whether these are mere eye-catching gimmicks or if these materials can be a serious competitor to the very well-established incumbent leather materials market must be answered.

Answers to this question with an extensive breakdown and analysis of commercial plant-based leathers, market players, and outlook alongside other competing alternative leather materials are available in IDTechEx's market report, 'Emerging Alternative Leathers 2024-2034: Technologies, Trends, Players'.

Full Story

Grosvenor Launches Net Zero Carbon Pathway to Curb Carbon Emissions Across North American Property Business
San Francisco, California

Grosvenor, an international property owner and developer with a 70+ year track record in North America, has launched its Pathway to Net Zero, a reductions-first approach to help the company achieve a projected 42% decrease in carbon emissions, relative to a 2021 baseline year, by 2030 and reach Net Zero by 2050.

The North American Net Zero Carbon Pathway directly supports Grosvenor's ambition to reduce carbon emissions in line with limiting global warming to 1.5°C, building on and accelerating the organization's progress in curbing its carbon footprint across its global business activities.

In North America, the company has been actively working to reduce its environmental impact and has publicly reported its consumption and carbon emission reduction numbers for over a decade.

Grosvenor signed the World Green Building Council's (WGBC) Net Zero Carbon Buildings Commitment in 2019 and has been reporting to the Global Real Estate Sustainability Benchmark (GRESB), an independent group that tracks ESG progress across 2,200 companies, for three years. In 2023, Grosvenor maintained a strong 4 Green Star rating for its Development portfolio with a score of 91 placing it 12 points above its benchmark average. The Investment portfolio scored 77, a 12-point increase since the firm's initial submission to GRESB in 2021.

Full Story

The Art of Living Revives Radha Kunj Lake: A Testament to Environmental Health
Bengaluru, India

Water pollution poses a significant threat to environmental and human health, with various sources such as residential, industrial, agricultural, and livestock activities contributing to its degradation. Traditional methodologies for addressing water pollution often fall short, necessitating innovative solutions. Nature based interventions have emerged as effective strategies for mitigating water pollution, leveraging the inherent power of natural elements like microorganisms, plants, and algae. Says Gurudev Sri Sri Ravi Shankar, "We need to protect the environment- this is our first and foremost duty as citizens of this world. If we take care of the environment, it will take care of us and bring us health, prosperity, and happiness.''

Amidst the tranquil landscape of The Art of Living International Centre in Bengaluru, lies Radha Kunj Lake, also known as Udipalya Kere, once faced with severe pollution issues, endangering aquatic life, and posing health risks to the surrounding ecosystem. To combat this challenge, a multi-faceted approach incorporating nature-based solutions was implemented in April 2023 by The Art of Living. Boulder checks were strategically installed along the stream to filter pollutants and facilitate natural filtration processes. Additionally, native vegetation and hyperaccumulator plants were reintroduced to absorb contaminants and restore ecological balance.

Microbial remediation techniques, such as bioremediation and phycoremediation, played a crucial role in detoxifying the water. Bio-bridges constructed with indigenous materials provided habitats for microbial communities, while diatomaceous algae were introduced to enhance the lake's natural cleansing abilities. Furthermore, aeration through fountain systems injected oxygen into the water, revitalising the aquatic habitat and promoting biodiversity.

Full Story

Groundbreaking Study Revolutionizes Type 2 Diabetes Management Through Fasting Mimicking Nutrition Technology
Los Angeles, California

L-Nutra, the premier nutri-technology company, has unveiled the results of a pioneering clinical trial, published in Diabetologia, which aims to redefine the approach to managing Type 2 Diabetes. Conducted over a 12-month period and compared to the current standard of care, the study assessed the impact of a Fasting Mimicking Diet (FMD) on glycemic control and medication reduction, delivering compelling evidence to support the integration of the FMD program into primary care management of Type 2 Diabetes.

Over 30 million people in the U.S. suffer from diabetes, and nearly 98 million have pre-diabetes. These striking numbers directly correlate with unhealthy lifestyles and medications that mostly slow disease progression rather than reversing it. This new data suggests a viable, nutrition-led intervention that enhances the effectiveness of the standard of care, allowing the possibility of diabetes regression to be within reach.

The research involved 100 Type 2 Diabetes patients with a BMI greater than 27 and HbA1C levels above 6.5%, who were either on standard care or treated with Metformin. This randomized, controlled, assessor-blinded trial introduces a new paradigm in diabetes management, focusing on "glycemic management,'' a new metric used to measure efficacy by medication reduction.

Full Story

Researchers Discover Novel Drug Candidate to Combat Fatty Liver Disease
Gwangju, South Korea

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a burgeoning global health concern, posing a significant threat to public health and escalating the burden on healthcare resources. Characterized by the accumulation of fat in the liver, MASLD increases the risk of progressing to more severe conditions such as metabolic dysfunction-associated steatohepatitis (MASH), which is marked by inflammation, ballooning, and potential fibrosis.

In response to the pressing need of effective treatments for these metabolic disorders, researchers led by Prof. Jin Hee Ahn from Gwangju Institute of Science and Technology (GIST) meticulously developed compound 11c, a novel peripheral 5HT2A antagonist. This research was made available online on January 20, 2024, and was published in Nature Communications, highlighting a significant therapeutic breakthrough. The compound showcased a promising profile and demonstrated efficacy in preclinical models, positioning it at the forefront of groundbreaking advancements in the field.

11c exhibits promising attributes, including robust biological activity and a favorable safety profile. Dr. Haushabhau Shivaji Pagire, first author and senior researcher at the Medicinal Chemistry Laboratory at GIST, emphasizes, "Our meticulous analyses have revealed a significant reduction in inflammatory and fibrosis markers, attesting to the potent anti-inflammatory and fibrotic effect of the compound. This action, targeting both inflammation and fibrosis, is a promising step forward in treating MASH."

Full Story

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